Breast etiology

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Data on known risk factors for human breast cancer are reviewed. The major predictors of risk are age, geographic area of residence, age at first birth, certain indicators of ovarian activity, history of benign breast disease, and familial history of breast cancer. Specific etiologic hypotheses are also reviewed, with consideration of the extent to which they explain, or are consistent with, the observed patterns of risk distribution.

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Unfortunately, we do not answer medical questions. Mutations in these genes raises risk of both breast and ovarian cancer. About one-third of patients with familial breast cancer have detectable BRCA gene mutations if one examines both genes completely, while almost all families with accumulation of both breast and ovarian cancer have detectable BRCA gene mutations.

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Each breast contains 15 to 20 lobes of glandular tissue, arranged like the petals of a daisy. The lobes are further divided into smaller lobules that produce milk for breast-feeding. Small tubes ducts conduct the milk to a reservoir that lies just beneath your nipple.

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For full functionality, it is necessary to enable JavaScript. Here are instructions how to enable JavaScript in your web browser. Healthline Media, Inc.

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Use the link below to share a full-text version of this article with your friends and colleagues. Learn more. Because of the recognized relationship between aging and the development of cancer, the authors have proposed that the rate and extent of involution may be important factors in the etiology of breast cancer.

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Studies have shown that your risk for breast cancer is due to a combination of factors. The main factors that influence your risk include being a woman and getting older. Most breast cancers are found in women who are 50 years old or older.

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Providing cutting-edge scholarly communications to worldwide, enabling them to utilize available resources effectively. We aim to bring about a change in modern scholarly communications through the effective use of editorial and publishing polices. Trivikram M Deshpande.

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Breast cancer is cancer that develops from breast tissue. Risk factors for developing breast cancer include being female, obesitylack of physical exercise, drinking alcoholhormone replacement therapy during menopauseionizing radiationearly age at first menstruationhaving children late or not at all, older age, prior history of breast cancer, and family history. The balance of benefits versus harms of breast cancer screening is controversial. A Cochrane review stated that it is unclear if mammographic screening does more good or harm.

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Breast cancer refers to the formation of malignant tumors in the breast tissue. The most common targets are beneath the arms, collar bones, in the chest behind the breast bones, and in the lymph nodes. A non-invasive form of early breast cancer is ductal carcinoma in situ DCISwhich means the cancer is in the cells that line the ducts, but has not spread through the walls of the ducts to the breast tissue.

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