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European Radiology. Microglandular adenosis is a very uncommon benign proliferative disorder of the breast that may mimic tubular carcinoma radiologically and pathologically. We describe the radiological features of this rare condition in a patient with BRCA 1 mutation.
Electronic address: mariapia. Microglandular adenosis MA of the breast, a benign glandular proliferation, was originally described approximately 35 years ago. The lesion is constituted by small glands, all of the same size.
Microglandular adenosis MGA of the breast is a pathological subtype of mammary adenosis. It is benign breast condition although can mimic a breast cancer particularly tubular breast carcinoma 3,5 both clinically, radiology and pathologically. Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys.
The definitive risk factors for Microglandular Adenosis of Breast are not well-understood. It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases ones chances of getting a condition compared to an individual without the risk factors.
Skip to search form Skip to main content. Microglandular adenosis of the breast. A clinicopathologic study of 11 cases with ultrastructural observations.
Benign conditions of the breast encompass a wide range of morphological features, from cystic lesions to changes characterized by epithelial proliferation with stromal fibrosis and sclerosis. Microglandular adenosis MA and atypical microglandular adenosis AMA are rare benign lesions that can mimic invasive carcinoma of the breast both clinically and on histopathological examination. Anatomic pathology examination of an ultrasound-guided biopsy specimen obtained in September revealed epithelial proliferation forming nest-like and cord-like structures with nuclear atypia. Immunohistochemical analysis was inconclusive but suggestive of infiltrating carcinoma.
Microglandular adenosis of the breast is a benign proliferative lesion, and is a rare subtype of adenosis. The pathologic findings and clinical symptoms can mimic those of breast cancer. Microglandular adenosis has been frequently associated with invasive carcinoma and in situ carcinoma of the breast.